ORCA Computing and SiC Systems Win 2025 HPC Innovation Excellence Award for Quantum-Accelerated Agentic AI
November 19 2025 -- ORCA and SiC Systems have announced their joint project, “Agentic AI for Biomanufacturing Optimization Using Hybrid Quantum–Classical HPC Systems,” has been selected as a winner of the 2025 HPC Innovation Excellence Award, presented by Hyperion Research. The HPC Innovation Excellence Awards program honors outstanding achievements that demonstrate the real-world value of HPC technologies, with the goal of showcasing scientific, engineering and economic impact across industries.
Developed in collaboration with the Technical University of Denmark (DTU) and Novo Nordisk, the project showcases a next-generation Agentic AI framework that integrates photonic quantum processors, GPU-accelerated HPC systems, and autonomous AI agents to optimize complex biomanufacturing workflows in real time.
The team’s Sense–Infer–Control (SIC) platform links multiscale digital twins with live process execution, enabling AI agents to autonomously analyze, infer, and tune bioprocesses with greater precision, stability, and reproducibility.
“This work demonstrates how Agentic AI can transform industrial bioprocessing,” said Seyed Soheil Mansouri, PhD, Co-Founder of SiC Systems and Associate Professor at the Technical University of Denmark (DTU). “By combining digital twins, automation, and quantum acceleration, we unlock new pathways for efficiency and scientific insight.”
“AI agents operating on quantum-enhanced infrastructure bring a powerful new paradigm to advanced manufacturing,” said Christopher Savoie, Co-Founder and CEO of SiC Systems. “This collaboration shows how real-time optimization can become both autonomous and explainable.”
“This award is an important recognition of how hybrid quantum–AI is delivering practical impact today,” said Dr. William Clements, Head of Applications and Software at ORCA Computing. “Our work with SiC Systems and DTU demonstrates how quantum photonics integrated with HPC can solve real, high-value problems in industry.”
Award winners were recognized and celebrated at the Hyperion HPC/AI Breakfast Briefing on November 18th 205 during the SC25 Conference.


